The Localised Surface Plasmon Resonance (LSPR) technique is used for label-free optical detection of biomolecular interactions in real time. This is a well-established biosensing technique with many benefits including portability, simplisity, high specificity and sensitivity which has found application in various fields such as drug discovery, material science and biosensors.
SPECTRUNA NR : compact imaging spectrophotometry system for nanoplasmonics and colloidal solution of plasmonic nanoparticles. Optional tandem quartz cuvette allows a real-time differential resonance peak detection. A low cost device for research and education with configuration that can be adapted to meet individual customer requirements.
SPECTRUNA LED : compact imaging spectrophotometry system for nanoplasmonics and colloidal solution of plasmonic nanoparticles. Optional tandem quartz cuvette allows a real-time differential resonance peak detection using stable LED illumination source.
SPECIFICATION
SPECTRUNA LED:
Source: high CRI LED
Detector: fast CMOS Camera
Spectral range 430 – 670nm
Temporal Resolution: up to 10-2 nm
Integrated temperature sensor: External temperature compensation
USB3.1 C-type: Data processing & Power supply
SPECTRUNA NR:
Source: Halogen Lamp
Detector: fast CMOS Camera
Spectral range 410 –800nm
Temporal Resolution: up to 10-2 nm
Integrated temperature sensor: External temperature compensation
USB3.1 C-type: Data processing
Extinction Spectra
LSPR : colloidal plasmonic nanoparticles
Differential measurements: horizontal configuration. Tandem cuvette.
Visual C++ control software: double channels
Measuring principle Transmission Diffraction Gratings spectrometer Measuring approach Multi-track Spectroscopy Imaging Spectroscopy Spectral range 410 – 800nm ( tunable on request) Spectral Resolution < 0.01nm (Temporal) Throughput Single channel, Reference channel Detector 2D CMOS Camera Sample injection method Cuvette Data processing S/W via USB3 port Dimension 56.5(w)x77(L)x31(H)mm x73(H)mm with cup Control software VisualC++, Power Requirements USB3.0 powered or External power supply
a complete spectrophotometer optimized for plasmonic nanoparticles applications. Its design based on imaging spectroscopy has the advantage to allow both conventional single-channel analysis for sample characterization and dual-channel mode for real time differential detection using vertical or horizontal configuration with tandem cuvettes. The device is paired with an analytics software designed to precisely detect and follow plasmonic peak position (up to 0.01 nm). The system is ideal for LSPR applications including nanoparticles size and composition characterization, biosensing, and real-time monitoring of nanoparticles functionalization.
Plasmonic Nanoparticles Resonance spectra
Real-time dynamic of SH-PEG nanoparticles functionalization
Resonance peak position dependence on the NPs solution temperature.
Signal stability with real-time and constant reference. 13nm Au NPs.